Methodological Flaws in the Chabot Trial of Pancreatic Enzymes for Cancer Therapy
نویسنده
چکیده
A trial of gemcitabine versus pancreatic enzymes for the treatment of pancreatic cancer reported an average survival time of 14 months for the chemotherapy group and 4.3 months for the enzyme group. Due to extensive missing information, readers of the paper reporting the trial would conclude that the study was valid. When this missing information is made available, as it is in the present report, it becomes evident that there were numerous serious methodological flaws in the study. No scientifically valid conclusions about the treatment of cancer with pancreatic enzymes can be reached from this study.
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